Use the Back button in your browser to see the other results of your search or to select another record.

Detailed Search Results

A trial of conditioning therapy in nocturnal enuresis
Forrester RM, Stein Z, Susser MW
Developmental Medicine and Child Neurology 1964 Apr;6(2):158-166
clinical trial
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

A controlled trial of conditioning by alarm and of amphetamine for the treatment of enuresis was planned. The experimental group was to consist of 118 enuretic school-children of 8 years and over, detected in a community survey, but only 37 could be enrolled for the trial; 57 had remitted spontaneously or improved before appointments could be made, 15 defaulted, and 9 were rejected as unsuitable. The 37 cases were allocated at random to the two treatments. Assessments were made six months later, by which time 4 further cases had been lost to the trial. Among 33 cases remaining, 16 on alarm and 17 on amphetamine, the results for the alarm were significantly better; this was more so among the 23 cases whose treatment was considered adequate. Amphetamine had no greater effect than the natural remission-rate. The significance of this result to theories of conditioning and of the mechanism of enuresis is discussed.

Full text (sometimes free) may be available at these link(s):      help