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Comparison of liquid and gaseous oxygen for domiciliary portable use
Lock SH, Blower G, Prynne M, Wedzicha JA
Thorax 1992 Feb;47(2):98-100
clinical trial
3/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

BACKGROUND: Liquid oxygen is available for portable use and may have advantages over gas cylinders. METHODS: The use and acceptability of liquid and gaseous oxygen was compared in 15 patients with chronic lung disease who had shown an improvement of at least 10% in assessments of exercise tolerance and breathlessness with standard portable oxygen. Gaseous and liquid portable oxygen were provided in random order for two eight week periods, and assessments consisted of six minute walking tests, lung function tests, chronic respiratory disease index questionnaires, and diary cards. RESULTS: The walking distance was not significantly affected by the weight of the equipment with either system. Patients used the liquid oxygen for significantly longer (23.5 hours a week) than the gas cylinder (10 hours a week). When using liquid oxygen patients went out of the house on average for 19.5 hours a week, compared with 15.5 hours a week with gaseous oxygen. The liquid oxygen system was preferred because the oxygen lasted longer, filling was easier, and the canister was easier to carry. CONCLUSIONS: Liquid oxygen for portable treatment may be of benefit in selected patients with chronic lung disease.
Reproduced with permission from the BMJ Publishing Group.

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