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Physical activity, total and regional obesity: dose-response considerations
Ross R, Janssen I
Medicine and Science in Sports and Exercise 2001 Jun;33(6 Suppl):S521-S527
systematic review

PURPOSE: This review was undertaken to determine whether exercise-induced weight loss was associated with corresponding reductions in total, abdominal, and visceral fat in a dose-response manner. METHODS: A literature search (Medline, 1966-2000) was performed using appropriate keywords to identify studies that consider the influence of exercise-induced weight loss on total and/or abdominal fat. The reference lists of those studies identified were cross-referenced for additional studies. RESULTS: Total fat. Review of available evidence suggested that studies evaluating the utility of physical activity as a means of obesity reduction could be subdivided into two categories based on study duration. Short-term studies (<= 16 wk, n = 20) were characterized by exercise programs that increased energy expenditure by values double (2,200 versus 1,100 kcal/wk) that of long-term studies (>= 26 wk, n = 11). Accordingly, short-term studies report reductions in body weight (-0.18 versus -0.06 kg/wk) and total fat (-0.21 versus -0.06 kg/wk) that are threefold higher than those reported in long-term studies. Moreover, with respect to dose-response issues, the evidence from short-term studies suggest that exercise-induced weight loss is positively related to reductions in total fat in a dose-response manner. No such relationship was observed when the results from long-term studies were examined. Abdominal fat. Limited evidence suggests that exercise-induced weight loss is associated with reductions in abdominal obesity as measured by waist circumference or imaging methods; however, at present there is insufficient evidence to determine a dose-response relationship between physical activity, and abdominal or visceral fat. CONCLUSION: In response to well-controlled, short-term trials, increasing physical activity expressed as energy expended per week is positively related to reductions in total adiposity in a dose-response manner. Although physical activity is associated with reduction in abdominal and visceral fat, there is insufficient evidence to determine a dose-response relationship.

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