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Random control clinical trial on effect of aerobic exercise training on weight management during radiation treatment for breast cancer
Drouin JS, Birk TJ, Wirth JC
Rehabilitation Oncology 2006;24(3):6-10
clinical trial
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

BACKGROUND AND PURPOSE: This study examined aerobic exercise training effects on kilograms (KG), body mass index (BMI), and skin caliper measures (SCM) in females undergoing radiation for breast cancer. SUBJECTS: 20 sedentary females (50.0 +/- 8.2 years old) with breast cancer (stage 0 (insitu) to III). METHODS: Participants were randomly assigned to moderate intensity aerobic exercise walking (AE) or placebo-stretching (PS) protocols performed 3 to 5 times during 7 weeks of radiation. KG, BMI, and SCM were measured one week before and after the radiation and activity regimens. Wilcoxon Signed-Rank Test assessed pre-post differences, Wilcoxon-Mann-Whitney U examined between group differences (p < 0.05). RESULTS: Baseline measures were not significantly different between groups. Following the interventions, KG, BMI, and SCM decreased significantly in AE participants (p < 0.01 for all measures) while PS changes were not significant. DISCUSSION AND CONCLUSION: Aerobic exercise appears to promote weight management during radiation for breast cancer.

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