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Effect of acupuncture and naloxone in patients with osteoarthritis pain. A sham acupuncture controlled study
Lundeberg T, Eriksson SV, Lundeberg S, Thomas M
The Pain Clinic 1991;4(3):155-161
clinical trial
4/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

The aim of this investigation was to assess the efficacy of different types of acupuncture and sham acupuncture in the management of chronic pain. Fifty-eight patients with chronic cervical osteoarthritis were randomized to either manual acupuncture, 2 or 80 Hz electroacupuncture or sham acupuncture. For sham acupuncture the needles were inserted superficially. The effect of naloxone (0.8 mg) was also evaluated. At all trials pain was assessed by visual analogue scales before and after treatment. These scales were separately used to rate the intensity (sensory component) and unpleasantness (affective component) of pain. The results of the present study show that acupuncture has a more pronounced effect on the affective than the sensorp component of pain. All modes of acupuncture produced significant pain reduction. Naloxone in low doses does not significantly alter pain perception in patients suffering pain from cervical osteoarthritis. Nor does it in these patients reduce the reduction of pain resulting from acupuncture. It was not possible to demonstrate any significant differences between the effect of manual versus electrical acupuncture or sham acupuncture in this group of patients.

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