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(Effect of Tai Chi exercise on blood pressure, plasma nitrogen monoxidum and endothelin in hypertensive patients) [Chinese - simplified characters]
Mao H-N, Sha P
Zhongguo Linchuang Kangfu [Chinese Journal of Clinical Rehabilitation] 2006 Dec 25;10(48):65-67
clinical trial
5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

AIM: To inquire the effects of doing Tai Chi (Chinese shadow-boxing) for 8 weeks on the blood pressure, plasma nitrogen monoxidum (NO) and endothelin (ET) of patients with hypertension. METHODS: The experiment was conducted from August to October 2005. Totally 62 retired staffs of Chang'an University suffered from primary hypertension lasted for one or two years' were selected. The investigation was on a voluntary participation. The 62 staffs were randomly divided into two groups: (1) Tai Chi group (n = 51): they did Tai Chi six times every week 1 hour each time for 8 weeks besides taking the hypotensive drug. The exercise prescription included 3 parts: warning-up stage for 15 minutes, exercise stage for 30 minutes and relaxation stage for 10 to 15 minutes. In the 30 minutes exercise of 24 posture Tai Chi, the patients should maintain the exercise intensity with maximum of oxygen-intaking at 50% to 60%. Also, they should keep their eating and living habits in the experimental period. (2) Control group (n = 11): they did not do any exercises and just maintained their eating and living habits. The blood pressure, NO and ET of the patients were measured before and after experiment. RESULTS: All the 62 patients were involved in the result analysis. (1) Blood pressure: the Tai Chi group was obviously lower than the index before exercise and the control group (diastolic pressure: 82.74 +/- 11.97, 93.66 +/- 13.72, 94.35 +/- 38.90 mmHg (1 mmHg = 0.133 kPa); systolic pressure: 140.49 +/- 23.55, 162.74 +/- 26.36, 163.89 +/- 67.63 mmHg, p < 0.01). (2) ET: the Tai Chi group was obviously lower than the index before exercise and the control group (43.82 +/- 10.98, 68.90 +/- 22.21, 65.93 +/- 27.28 ng/L, p < 0.01). (3) NO level: the Tai Chi group was obviously higher than that before exercise and the control group (22.35 +/- 7.80, 17.72 +/- 19.89, 19.68 +/- 10.42 mmol/L, p < 0.05). (4) No obvious change in each index was found in the control group during the experiment. CONCLUSION: Doing Tai Chi can decline the blood pleasure and ET level, and raise the NO index of patients with hypertension.

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