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The effects of knee extensor and flexor muscle training on the timed-up-and-go test in individuals with rheumatoid arthritis
McMeeken J, Stillman B, Story I, Kent P, Smith J
Physiotherapy Research International 1999;4(1):55-67
clinical trial
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

BACKGROUND AND PURPOSE: Rheumatoid arthritis frequently results in functional impairment. This study investigated the effect of a specific exercise regimen on function. METHOD: A randomized controlled assessor-blinded (N = 36) compared the effect of knee extensor and flexor muscle training on pain, the Timed Up and Go (TUG) test and the Health Assessment Questionnaire in subjects with non-acute rheumatoid arthritis. RESULTS: Knee extensor and flexor muscle training increased isokinetic torques at speeds of 60 degrees/sec-1 and 120 degrees/sec-1 as measured by an isokinetic dynamometer (p = 0.02 to 0.003). The experimental group experienced a reduction in pain (p = 0.03), an improvement in TUG time (p = 0.01) and in function as measured by the Health Assessment Questionnaire (p = 0.04). CONCLUSIONS: Specific knee muscle training can be administered safely in people with non-acute rheumatoid arthritis, and may produce functional benefits.

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