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Endotracheal suctioning in adults with head injury |
Rudy EB, Turner BS, Baun M, Stone KS, Brucia J |
Heart & Lung 1991 Nov-Dec;20(6):667-674 |
clinical trial |
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: No. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
The purpose of this study was to determine the method of endotracheal suctioning (ETS) that resulted in the least compromise to the cerebrovascular status of adult patients with severe head injuries. A two-group (two versus three ETS), two-protocol (100% tidal volume (VT) versus 135% VT) design was used. The dependent variables were mean intracranial pressure (MICP), mean arterial pressure (MAP), cerebral perfusion pressure (CPP), heart rate (HR), and oxygen saturation (SaO2). By random assignment, 14 subjects were in the two-ETS group and 16 subjects were in the three-ETS group. Intracranial pressure response to ETS in these patients with head injury can be characterized as falling into three patterns: (1) a rise in baseline beginning with ETS and continuing throughout the ETS sequences; (2) intracranial pressure spiking during the suctioning component of the protocol; (3) a combination of both a rising baseline and spiking. There was a significant (p <= 0.001) increase from baseline for both two- and three-ETS groups with both hyperoxygenation protocols (100% VT versus 135% VT) for MICP, MAP, HR, and CPP. No significant difference was found for SaO2 for either of the protocols regardless of number of suction passes. No significant differences were found between two- and three-ETS groups for any of the dependent variables. All groups, however, regardless of number of suction passes, demonstrated a cumulative increase in MICP, MAP, and CPP with each consecutive suction sequence. We conclude that patients with severe closed head injury (Glasgow Coma Scale score -8), particularly those who respond with a spiking intracranial pressure pattern, are at risk for periods of cerebral hypertension during an ETS procedure. In some patients the response to ETS is cumulative, making mulitiple suction passes particularly dangerous. Preoxygenation of patients with 100% oxygen is not adequate to prevent extreme rises in MICP. It is recommended that the number of suction passes be limited to two per procedure, combined with adequate preoxygenation routine.
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