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The effectiveness of massage with and without dimethyl sulfoxide in preventing pressure ulcers: a randomized, double-blind cross-over trial in patients prone to pressure ulcers
Duimel-Peeters IGP, Halfens RJG, Ambergen AW, Houwing RH, Berger MPF, Snoeckx LHE
International Journal of Nursing Studies 2007 Nov;44(8):1285-1295
clinical trial
3/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

BACKGROUND: Although guidelines advise against massage, it is one of the methods widely regarded and used by nurses to prevent pressure ulcers (PU). OBJECTIVES: The purpose of this study was to examine the effectiveness of different variations of massage in preventing pressure ulcers. METHODS: A randomized, double-blind cross-over design, in which patients of nursing homes who are prone to PU underwent two of the three possible interventions; 'position changes only', 'massaging with an indifferent cream' and 'massaging with a dimethyl sulfoxide (DMSO) cream'. RESULTS: The results of three interventions did not differ significantly. DMSO did not fulfil the expectations raised by literature and a previous pilot-study.
With permission from Excerpta Medica Inc.

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