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Relaxation therapy for essential hypertension: a Veterans Administration Outpatient study
Brauer AP, Horlick L, Nelson E, Farquhar JW, Agras WS
Journal of Behavioral Medicine 1979 Mar;2(1):21-29
clinical trial
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

Twenty-nine patients who had been treated with antihypertensive medication for at least the preceding 6 months were randomly assigned to (1) therapist-conducted, face-to-face progressive, deep-muscle relaxation training for 10 weekly sessions, or (2) progressive deep-muscle relaxation therapy conducted mainly by home use of audio cassettes, or (3) nonspecific individual psychotherapy for 10 weekly sessions. No differences between the groups were found immediately after therapy; however, the therapist-conducted relaxation therapy group showed the greatest changes: -17.8 mmHg systolic, -9.7 mmHg diastolic at 6 months follow-up. Some significant trends in results among the three therapists were also found. No correlation existed between blood pressure changes and changes in dopamine-beta-hydroxylase (DbH) levels.

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