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The benefits of exercise combined with physiotherapy in the treatment of adults with cystic fibrosis
Bilton D, Dodd ME, Abbot JV, Webb AK
Respiratory Medicine 1992 Nov;86(6):507-511
clinical trial
4/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

The impact of exercise, physiotherapy, and combinations of exercise and physiotherapy upon sputum expectoration were compared in 18 adults with cystic fibrosis. Any treatment which included physiotherapy either alone or in combination with exercise produced a significantly higher sputum weight during treatment time than did exercise alone (p < 0.01). This trend was true for both high (> 35 g in 24 h) and low (< 35 g in 24 h) sputum producers (p < 0.05). There were no significant changes in FEV1 and FVC 30 min after any treatment. The treatment option preferred by patients to continue at home was exercise followed by physiotherapy (p < 0.001). Exercise alone was less productive than the other three modalities in clearing sputum (p < 0.001).

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