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(Extracorporeal magnetic innervation in the treatment of urinary incontinence after radical prostatectomy) [Chinese - simplified characters]
Liu F, Yao L-P, Mai H-X, Liu H-L, Yuan J-L, Wang F-L, Nan L-N, Wang H
Zhongguo Zuzhi Gongcheng yu Linchuang Kangfu [Journal of Clinical Rehabilitative Tissue Engineering Research] 2008 Apr 22;12(17):3289-3292
clinical trial
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

BACKGROUND: Extracorporeal magnetic innervation (ExMI) has been developed for the stimulation of pelvic floor muscles. It is a novel therapy for urinary incontinence. To date, there is only one report from abroad about the stimulation of pelvic floor muscles by ExMI for urinary incontinence following radical prostatectomy. OBJECTIVE: To compare and analyze the treatment effect of ExMI and pelvic floor muscle exercise (PFME) on urinary incontinence after radical prostatectomy. DESIGN, TIME AND SETTING: The randomized controlled clinical trial was performed at the Department of Urology, Xijing Hospital of Fourth Military Medical University of Chinese PLA from February 2005 to February 2007. PARTICIPANTS: Twenty-four patients with urinary incontinence after radical prostatectomy were randomly assigned to ExMI group and PFME group (n = 12). METHODS: For ExMI group, the frequency of the pulse field was 10 Hz for 10 minutes, followed by a 3 minutes rest and a second treatment at 50 Hz for 20 minutes. The treatment lasted for 30 minutes every time and twice a week. The patients in PFME group were advised to do the exercise of anal contraction and relaxation, anal sphincter contraction similar to sudden interruption of urination by keeping abdominal muscle relaxation. The contraction was for 3 seconds each time followed by a 3-second rest, 20 minutes once, 3 times a day for successive 6 weeks. MAIN OUTCOME MEASURES: The therapeutic effect was evaluated by Quality-of-Life Scale and the International Continence Inquiring Committee Questionnaire Short Form (ICI-Q-SF). RESULTS: Twenty-four patients were all included in final analysis. There were no significant differences in ICI-Q-SF scores between two groups before treatment. After one month of treatment, both scores for the Quality-of-Life Scale and ICI-Q-SF were decreased (p < 0.05 to 0.01), and there were no significant differences between two groups. After 3 months and 6 months of treatment, the scores of two scales continued to decrease, and those of ExMI group were significantly lower than those of PFME group (p < 0.05). No complications were noted in any of the groups. CONCLUSION: ExMI is superior over PFME in treating urinary incontinence after radical prostatectomy.

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