Use the Back button in your browser to see the other results of your search or to select another record.

Detailed Search Results

Effect of 4 weeks of aerobic or resistance exercise training on arterial stiffness, blood flow and blood pressure in pre- and stage-1 hypertensives [with consumer summary]
Collier SR, Kanaley JA, Carhart R Jr, Frechette V, Tobin MM, Hall AK, Luckenbaugh AN, Fernhall B
Journal of Human Hypertension 2008 Oct;22(10):678-686
clinical trial
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

The benefits of aerobic exercise (AE) training on blood pressure (BP) and arterial stiffness are well established, but the effects of resistance training are less well delineated. The purpose of this study was to determine the impact of resistance versus aerobic training on haemodynamics and arterial stiffness. Thirty pre- or stage-1 essential hypertensives (20 men and 10 women), not on any medications, were recruited (age 48.2 +/- 1.3 years) and randomly assigned to 4 weeks of either resistance (RE) or AE training. Before and after training, BP, arterial stiffness (pulse wave velocity (PWV)) and vasodilatory capacity (VC) were measured. Resting systolic BP (SBP) decreased following both training modes (SBP: RE, pre 136 +/- 2.9 versus post 132 +/- 3.4; AE, pre 141 +/- 3.8 versus post 136 +/- 3.4 mmHg, p = 0.005; diastolic BP: RE, pre 78 +/- 1.3 versus post 74 +/- 1.6; AE, pre 80 +/- 1.6 versus post 77 +/- 1.7 mmHg, p = 0.001). Central PWV increased (p = 0.0001) following RE (11 +/- 0.9 to 12.7 +/- 0.9 m/s) but decreased after AE (12.1 +/- 0.8 to 11.1 +/- 0.8 m/s). Peripheral PWV also increased (p = 0.013) following RE (RE, pre 11.5 +/- 0.8 versus post 12.5 +/- 0.7 m/s) and decreased after AE (AE, pre 12.6 +/- 0.8 versus post 11.6 +/- 0.7 m/s). The VC area under the curve (VCauc) increased more with RE than that with AE (RE, pre 76 +/- 8.0 versus post 131.1 +/- 11.6; AE, pre 82.7 +/- 8.0 versus post 110.1 +/- 11.6 ml per min per s per 100 ml, p = 0.001). Further, peak VC (VCpeak) increased more following resistance training compared to aerobic training (RE, pre 17 +/- 1.9 versus post 25.8 +/- 2.1; AE, pre 19.2 +/- 8.4 versus post 22.9 +/- 8.4 ml per min per s per 100 ml, p = 0.005). Although both RE and AE training decreased BP, the change in pressure may be due to different mechanisms.
Reprinted by permission from Journal of Human Hypertension, Macmillan Publishers Ltd.

Full text (sometimes free) may be available at these link(s):      help