The authors used the meta-analytic approach to examine the effects of aerobic exercise on non-high-density lipoprotein cholesterol (non-HDL-C) in children and adolescents. Thirteen non-HDL-C outcomes in 404 males and females (221 exercise, 183 control) were available for pooling. Random-effects modeling yielded a nonstatistically significant exercise minus control group reduction of 0.61% in non-HDL-C (+/- SEM, -0.7 +/- 2.4 mg/dL, 95% confidence interval (CI) -5.4 to 5.0 mg/dL). A statistically significant decrease of 7% was found for percent body fat (+/- SEM, -2.1 +/- 0.5%, 95% CI -3.0 to -1.2%) as well as an 8% increase in aerobic capacity (+/- SEM, 3.4 +/- 1.0 mL/kg/min, 95% CI 1.4 to 5.3 mL/kg/min), both secondary outcomes of the study. It was concluded that aerobic exercise does not reduce non-HDL-C but does improve percent body fat and aerobic capacity in children and adolescents. However, a need exists for additional studies on this topic.

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