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Massage therapy reduces hospital stay and occurrence of late-onset sepsis in very preterm neonates
Mendes EW, Procianoy RS
Journal of Perinatology 2008 Dec;28(12):815-820
clinical trial
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: To study the effect of maternal massage therapy on hospital stay in very-low-birth-weight infants who were already submitted to skin-to-skin care. STUDY DESIGN: A randomized study was performed including infants of birth weight >= 750 and <= 1,500 g and gestational age <= 32 weeks. The exclusion criteria were as follows: death before completing 48 h and presence of major malformations. Neonates were divided into intervention group (IG) (standard care plus maternal massage) and control group (CG). Anthropometric data were always verified by a person blind to the group to which the newborn belonged. Maternal massage was performed four times a day on the face and limbs. Passive exercises of upper and lower limbs were also done by the mothers. RESULT: A total of 104 newborns were included, 52 in each group. Both groups were similar in gestational age (IG 29.7 +/- 1.6; CG 29.4 +/- 1.6 weeks), birth weight (IG 1,186 +/- 194; CG 1,156 +/- 198 g), gender, number of small-for-gestational-age infants, SNAPPE-II, deaths, gains in weight, length and head circumference. Incidence of late-onset sepsis was significantly lower in the intervention group (IG 10.8%, n = 5; CG 38.3%, n = 18; p = 0.005). IG was discharged from the hospital 7 days before CG (IG 42, confidence interval (CI) 95% 38 to 46; CG: 49, CI 95% 42 to 56), and presented 1.85 hazard ratio (CI 95% 1.09 to 3.13; p = 0.023) for early discharge. CONCLUSION: Maternal massage therapy in very-low-birth-weight infants decreases the length of hospital stay and the incidence of late-onset neonatal sepsis.
Reprinted by permission from Journal of Perinatology, Macmillan Publishers Ltd.

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