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| Short-term effects of aerobic exercise on functional capacity, fatigue, and quality of life in patients with post-polio syndrome [with consumer summary] |
| Oncu J, Durmaz B, Karapolat H |
| Clinical Rehabilitation 2009 Feb;23(2):155-163 |
| clinical trial |
| 6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
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OBJECTIVE: To investigate and compare the impact of hospital and home exercise programmes on aerobic capacity, fatigue, and quality of life in patients with post-polio syndrome. DESIGN: A prospective, randomized controlled trial. SETTING: Department of Physical Medicine and Rehabilitation, University Hospital. SUBJECTS: Thirty-two patients were divided into two groups for either hospital- or home-based aerobic exercise programme. MAIN OUTCOME MEASURES: Patients were assessed before and after the rehabilitation programme, with respect to functional capacity (pVO2), fatigue (Fatigue Severity Scale, Fatigue Impact Scale) and quality of life (Nottingham Heath Profile). RESULTS: After the exercise programme, improvement was observed in the hospital exercise group compared to a pre-exercise period in all Nottingham Heath Profile scores (except sleep scores), pVO2, Fatigue Severity Scale and Fatigue Impact Scale (cognitive, physical, psychosocial, total) (p < 0.05). In contrast, in the home exercise group a decrease was observed in pVO2 scores after the rehabilitation programme, compared to a pre-rehabilitation period (p < 0.05). In addition, a significant improvement was observed in the home exercise group after the rehabilitation programme in all parameters excluding Fatigue Impact Scale-physical, Fatigue Impact Scale-psychosocial, and Nottingham Heath Profile-sleep (p < 0.05). When the two exercise groups were compared, improvement was observed in the hospital exercise group compared to the home exercise group in pVO2 and Fatigue Severity Scale-total, Fatigue Impact Scale-physical, Fatigue Impact Scale-psychosocial, Fatigue Impact Scale-total, and Nottingham Heath Profile-energy scores (p < 0.05). CONCLUSION: Fatigue and quality of life were both improved in the home and hospital exercise groups. An increase was also found in the functional capacity in the hospital exercise group. A regular exercise programme is beneficial to patients with post-polio syndrome.
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