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Interval training versus continuous training in patients with chronic obstructive pulmonary disease
Mador MJ, Krawza M, Alhajhusian A, Khan AI, Shaffer M, Kufel TJ
Journal of Cardiopulmonary Rehabilitation and Prevention 2009 Mar-Apr;29(2):126-132
clinical trial
7/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

PURPOSE: The purpose of this study was to compare the effects of interval training (IT) and continuous steady-pace training (CT) in patients with COPD. METHODS: Patients (n = 21) (mean forced expiratory volume in 1 second (FEV1) 44.6% +/- 13.9%) were randomized to IT, and 20 patients (mean FEV1 = 41.7% +/- 12.6%) to CT. Outcome measures included 6-minute walk distance, maximal work capacity, endurance exercise time during constant workload exercise at 60% to 70% of maximal work capacity, and quality of life including fatigue and dyspnea. Participants exercised 3 times per week for 8 weeks, and total work was the same for both training regimens. RESULTS: Significant improvement in mean score was observed in each variable within each of the 2 groups: 6-minute walk distance (IT = 158 +/- 178 ft, CT = 106 +/- 165 ft); maximal work capacity (IT = 10.0 +/- 13.0 W, CT = 11.5 +/- 13.1 W); endurance exercise time (IT = 15.0 +/- 12.5 minutes, CT = 18.7 +/- 10.6 minutes); and quality of life domains, fatigue (IT = 3.1 +/- 3.0, CT = 2.8 +/- 4.7), and dyspnea (IT = 4.4 +/- 5.3, CT = 5.4 +/- 5.1). There was no significant difference in the extent of improvement between the 2 training regimens for any of the outcome variables. CONCLUSION: Compared with CT, IT was well tolerated and produced similar improvements in exercise performance and quality of life.
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