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Ein neuer weg in der thromboseprophylaxe: intermittierende sequentielle beinkompression mit hohen drucken (New method of preventing thrombosis: intermittent sequential high-pressure leg compression) [German]
Muhe E
Deutsche Medizinische Wochenschrift 1982 Jul 16;107(28):1092-1095
clinical trial
4/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: No; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

The effect of sequential pneumatic leg compression on venous flow velocity was studied in 25 patients. At the usual pressures of 35 to 55 mmHg, venous flow velocity was only 175% of control value, but 366% when pressures were between 90 and 100 mmHg. The incidence of postoperative thrombosis was studied on three groups of patients. In 24 patients, receiving sequential compression prophylaxis with 90 to 100 mmHg, there was one case of thrombosis, while there were three cases among the 25 patients with 35 mmHg compression and three in the 25 receiving 5,000 unit of heparin three times daily. Sequential intermittent compression with high pressures, ten compression cycles three times daily, is recommended for all patients unable to undertake active prophylactic measures. An absolute indication exists in those patients which can no be mobilised and those in whom there are additional contraindications to the use of anticoagulants. Sequential compression is no alternative to antithrombosis stockings. These must be worn from the day of hospitalisation until discharge, also during the period of pneumatic compression.

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