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Zur intervalltherapie der migrane mit laserakupunktur -- klinische und elektrophysiologische parameter (Laser acupuncture in migraine therapy -- methodological considerations and results of a randomized, controlled clinical and electrophysical study) [German]
Ho H, Kropp P, Wallasch T, Niederberger U, Weinschutz T
Akupunktur 1999;27(3):159-170
clinical trial
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

Acupuncture is more and more used in the treatment of migraine. In this study responder and non-responder rates for laser-acupuncture in migraine prophylaxis were examined. The treatment was carried out in a controlled design. After exclusion of symptomatic headache forms through our pain clinic 52 patients were randomized to two different treatment groups. The data were assessed by analysis of variance as well as nonparametric statistics and time-series analysis. Over all there was a statistically significant therapeutic effect of acupuncture treatment up to one year as shown by the reduction of migraine attacks and therefore it is a useful interval therapeutical agent for migraine. Compaired to the needle-acupuncture there was no significant reduction of the Contingent Negative Variation (CNV) a slow EEC-potential in the laser groups. Further studies for understanding these mechanism should be carried out.

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