INTRODUCTION: Nausea and vomiting are the most common disorders of digestive system in the pregnancy. This study was done to evaluate the effects of acupressure in reducing the severity of nausea and the episodes of vomiting in primigravida women (10 to 16 gestational ages). METHODS: In this clinical-trial study, 100 primigravida women with nausea and vomiting in gestational age of 10 to 16 weeks were randomly selected and divided in two groups, 50 women in the acupressure group and 50 women in the placebo group. Age, education, profession, BMI, gestational age, nausea and vomiting were matched in both groups. Treatment lasted for 4 days in both groups. In the acupressure group sea bands were placed on neiguan point on hands but in placebo group sea bands were placed on points other than the neiguan point. Then, daily severity of nausea and vomiting were recorded during treatment period. The data were analyzed by SPSS software (12 versions), Chi-square, t-test, Mann Whitney and Will Kaksun tests. RESULTS: There was not significant difference in the severity of nausea and frequency of vomiting before treatment in two groups. Severity of nausea and frequency of vomiting decreased significantly after treatment in acupressure group (p = 0.60 and p = 0.55 respectively). CONCLUSION: This study showed that the acupressure (by sea-bands that is free of side effects and economical) is effective in reducing severity of nausea and frequency of vomiting in pregnancy.

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