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Efficacy of P6 acupressure in the treatment of nausea and vomiting during pregnancy
O'Brien B, Relyea MJ, Taerum T
American Journal of Obstetrics and Gynecology 1996 Feb;174(2):708-715
clinical trial
7/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: Our purpose was to investigate the efficacy of P6 acupressure in reducing or relieving symptoms of nausea with or without vomiting and retching during pregnancy. STUDY DESIGN: Symptomatic pregnant volunteers (n = 161) participated in a 7-day community-based clinical trial. All participants were assigned to one of three groups (ie, P6 acupressure, placebo (acupressure bands inappropriately placed), or control) on the basis of a process of blocked randomization. Data were analyzed by error bar charts and analysis of variance of difference scores. RESULTS: Of 161 women, 149 (92.5%) completed the protocol. Irrespective of group assignment, participants reported significant decreases in nausea (p < 0.0009) and vomiting or retching (p < 0.0009). However, there was no differential treatment effect as a result of acupressure. CONCLUSION: There was no apparent medical benefit from the use of P6 acupressure. Our findings differ from other recently published studies that did not include a control group.
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