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Combined aerobic and resistance exercise training improves functional capacity and strength in CHF
Maiorana A, O'Driscoll G, Cheetham C, Collis J, Goodman C, Rankin S, Taylor R, Green D
Journal of Applied Physiology 2000 May;88(5):1565-1570
clinical trial
4/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

This study examined the effect of a novel circuit weight training (CWT) program on cardiorespiratory fitness, muscular strength, and body composition in 13 patients with chronic heart failure (CHF), using a prospective randomized crossover protocol. Peak exercise oxygen uptake (VO2peak) increased after the 8-wk CWT program (19. 5 +/- 1.2 versus 22.0 +/- 1.5 ml/kg/min, p < 0.01), as did exercise test duration (15.2 +/- 0.9 versus 18.0 +/- 1.1 min, p < 0.001). Submaximal exercise heart rate was lower after training at 60 and 80 W (121 +/- 3 versus 134 +/- 5 beats/min, p < 0.01) as was rate pressure product, whereas ventilatory threshold increased, from 52 +/- 3 to 58 +/- 3% of VO2peak (p < 0.05). CWT also increased maximal isotonic voluntary contractile strength for seven different muscle groups, from 392 to 462 kg (p = 0.001). CWT, an exercise prescription specifically targeting peripheral abnormalities in CHF, improves functional capacity and muscular strength in these patients.

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