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Improvement of the lipid profile with exercise in obese children: a systematic review [with consumer summary] |
Escalante Y, Saavedra JM, Garcia-Hermoso A, Dominguez AM |
Preventive Medicine 2012 May 1;54(5):293-301 |
systematic review |
OBJECTIVE: The objective of this systematic review was to assess the effectiveness of different physical exercise interventions on the lipid profile (high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), and triglycerides (TG)) of obese children. METHOD: A computerized search was made of seven databases using keywords. Effect sizes (ES) and 95% confidence intervals were calculated, and the heterogeneity (I2) of the studies was estimated using Cochran's Q-statistic applied to the effect size means. The studies were grouped according to the intervention program-aerobic alone or combined (aerobic fitness, strength, and flexibility). RESULTS: Seven studies were selected for review as satisfying the inclusion criteria. Six were randomized controlled trials (n = 318) and one was a controlled clinical trial (groups not randomly assigned) (n = 38). The main cumulative evidence indicates that the programs based on aerobic exercise alone have a moderate (ES -0.49; I2 = 87) and a large effect (ES -0.55; I2 = 77) on LDL-C and TG concentrations, respectively; and the programs based on combined exercise have a moderate effect (ES 0.50; I2 = 0) on HDL-C concentration. CONCLUSIONS: The programs based on aerobic exercise (60 min, 3 times/week, <= 75% maximum heart rate) improve the LDL-C and TG concentrations. Moreover, the programs based on combined exercise (>= 60 min, > 75% maximum heart rate) also improve the HDL-C concentration.
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