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Effects of selected aerobic exercises on the depression and concentrations of plasma serotonin in the depressed female students aged 18 to 25
Hemat-Far A, Shahsavari A, Mousavi SR
The Journal of Applied Research 2012;12(1):47-52
clinical trial
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

The aim of this study was to investigate rates of depression and plasma serotonin concentration in depressed female students as affected by eight weeks aerobic exercises. 20 female students with moderate levels of depression were selected by using Beck Depression Inventory (BDI), and divided into two experimental and control groups randomly. At the beginning measurement of plasma serotonin concentration was done of the subjects, and then the experiment group were affected by aerobic exercises (periodic) with 65 to 60% of maximum heart rate (HRmax) for eight weeks (three sessions per week). Study variables were measured 96 hours after the last exercises session. Results showed that levels of depression significantly decreased in experimental group. There was no significant difference between the two groups in terms of plasma serotonin concentration. Moreover significant relationship between plasma serotonin and depression were observed in both groups.

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