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Neutral wrist splinting in carpal tunnel syndrome: a 3- and 6-month clinical and neurophysiologic follow-up evaluation of nightonly splint therapy
Premoselli S, Sioli P, Grossi A, Cerri C
Europa Medicophysica [Mediterranean Journal of Physical and Rehabilitation Medicine] 2006 Jun;42(2):121-126
clinical trial
5/10 [Eligibility criteria: Yes; Random allocation: No; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

AIM: The aim of the study was to evaluate the long-term efficacy of night-only splint wear therapy for carpal tunnel syndrome (CTS). METHODS: We conducted a randomized case-control trial with evaluation after three and six months of follow-up of outpatients with mild, recent onset symptoms of CTS recruited from the department clinic. Fifty patients (50 hands) were enrolled, of which 36 completed the study at 6 months. The case group utilized a thermoplastic neutral wrist splint for night-only wear. Outcome measures were instrumental parameters (sensory and motor nerve conduction velocity), symptom and function alterations (as measured by Levine's self-administered questionnaire), clinical parameters (pressure-provocative and Phalen tests). RESULTS: Improvements were observed in Levine's symptom status score at the three-month (p = 0.001) and the six-month (p = 0.001) follow-up visits, in functional score (p = 0.0001) and (p = 0.0004), in median distal sensory latency (p = 0.01) and (p = 0.02), in pressure-provocative test outcome (p = 0.01) and (p = 0.003), in Phalen test outcome (p = 0.04) and (p = 0.05) respectively. CONCLUSION: Symptom relief and neurophysiological improvement after night-only splint wear therapy lasted up to the six-month follow-up visit.

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