PURPOSE: The purpose of this review is to evaluate the literature related to mobilization of the critically ill patient with an emphasis on functional outcomes and patient safety. METHODS: We searched the electronic databases of PubMed, CINAHL, Medline (Ovid), and the Cochrane Library for a period spanning 2000 to 2011. Articles used in this review included randomized and nonrandomized clinical trials, prospective and retrospective analyses, and case series in peer-reviewed journals. Sackett's levels of evidence were used to classify the current literature to evaluate the strength of the outcomes reported. RESULTS: Fifteen studies met inclusion criteria and were reviewed. According to Sackett's levels of evidence, 9 studies were level 4 evidence, one study was level 3, 4 studies were level 2, and one study was level one evidence. Ten studies pertained to patient safety/feasibility and 10 studies pertained to functional outcomes with 5 fitting into both categories. CONCLUSION: A search of the scientific literature revealed a limited number of studies that examined the mobilization of critically ill patients in the intensive care unit. However, literature that does exist supports early mobilization and physical therapy as a safe and effective intervention that can have a significant impact on functional outcomes.

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