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Active video games: the mediating effect of aerobic fitness on body composition
Maddison R, Mhurchu CN, Jull A, Prapavessis H, Foley LS, Jiang Y
The International Journal of Behavioral Nutrition and Physical Activity 2012 May 3;9(54):Epub
clinical trial
3/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

BACKGROUND: Increased understanding of why and how physical activity impacts on health outcomes is needed to increase the effectiveness of physical activity interventions. A recent randomized controlled trial of an active video game (PlayStation EyeToy) intervention showed a statistically significant treatment effect on the primary outcome, change from baseline in body mass index (BMI), which favored the intervention group at 24 weeks. In this short paper we evaluate the mediating effects of the secondary outcomes. OBJECTIVE: To identify mediators of the effect of an active video games intervention on body composition. METHODS: Data from a two-arm parallel randomized controlled trial of an active video game intervention (n = 322) were analyzed. The primary outcome was change from baseline in BMI. A priori secondary outcomes were considered as potential mediators of the intervention on BMI, including aerobic fitness (VO2max), time spent in moderate-to-vigorous physical activity (MVPA), and food snacking at 24 weeks. RESULTS: Only aerobic fitness at 24 weeks met the conditions for mediation, and was a significant mediator of BMI. CONCLUSION: Playing active video games can have a positive effect on body composition in overweight or obese children and this effect is most likely mediated through improved aerobic fitness. Future trials should examine other potential mediators related to this type of intervention. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry website http://www.anzctr.org.au study ID number ACTRN12607000632493.

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