Use the Back button in your browser to see the other results of your search or to select another record.

Detailed Search Results

2012 Brazilian Society of Rheumatology consensus for the treatment of rheumatoid arthritis
da Mota LM, Cruz BA, Brenol CV, Pereira IA, Rezende-Fronza LS, Bertolo MB, de Freitas MV, da Silva NA, Louzada-Junior P, Giorgi RD, Lima RA, da Rocha Castelar Pinheiro G [Brazilian Society of Rheumatology]
Revista Brasileira de Reumatologia [Brazilian Journal of Rheumatology] 2012 Mar-Apr;52(2):152-174
practice guideline

OBJECTIVE: to elaborate recommendations for the treatment of rheumatoid arthritis in Brazil. METHOD: literature review with articles' selection based on evidence and the expert opinion of the Rheumatoid Arthritis Committee of the Brazilian Society of Rheumatology. RESULTS AND CONCLUSIONS: (1) The therapeutic decision should be shared with the patient; (2) immediately after the diagnosis, a disease-modifying antirheumatic drug (DMARD) should be prescribed, and the treatment adjusted to achieve remission; (3) treatment should be conducted by a rheumatologist; (4) the initial treatment includes synthetic DMARDs; (5) methotrexate is the drug of choice; (6) patients who fail to respond after two schedules of synthetic DMARDs should be assessed for the use of biologic DMARDs; (7) exceptionally, biologic DMARDs can be considered earlier; (8) anti-TNF agents are preferentially recommended as the initial biologic therapy; (9) after therapeutic failure of a first biologic DMARD, other biologics can be used; (10) cyclophosphamide and azathioprine can be used in severe extra-articular manifestations; (11) oral corticoid is recommended at low doses and for short periods of time; (12) non-steroidal anti-inflammatory drugs should always be prescribed in association with a DMARD; (13) clinical assessments should be performed on a monthly basis at the beginning of treatment; (14) physical therapy, rehabilitation, and occupational therapy are indicated; (15) surgical treatment is recommended to correct sequelae; (16) alternative therapy does not replace traditional therapy; (17) family planning is recommended; (18) the active search and management of comorbidities are recommended; (19) the patient's vaccination status should be recorded and updated; (20) endemic-epidemic transmissible diseases should be investigated and treated.

Full text (sometimes free) may be available at these link(s):      help

Additional document(s) available for this guideline: