AIMS: Our study's purpose was to perform a systematic review to assess the effect of supervised exercise interventions on lipid profiles and blood pressure control. METHODS: We searched electronic databases and selected studies that evaluated the effect of supervised exercise intervention on cardiovascular risk factors in adult people with type 2 diabetes. We used random effect models to derive weighted mean differences of exercise on lipid profiles and blood pressure control. RESULTS: Forty-two RCTs (2808 subjects) met inclusion criteria and are included in our meta-analysis. Structured exercise was associated with a change in systolic blood pressure (SBP) of -2.42mmHg (95% CI -4.39 to -0.45mmHg), diastolic blood pressure (DBP) of -2.23mmHg (95% CI -3.21 to -1.25mmHg), high-density lipoprotein cholesterol (HDL-C) of 0.04mmol/L (95% CI 0.02-0.07mmol/L), and low-density lipoprotein cholesterol (LDL-C) of -0.16mmol/L (95% CI -0.30 to -0.01mmol/L). Heterogeneity was partially explained by age, dietary co-intervention and the duration and intensity of the exercise. CONCLUSIONS: Supervised exercise is effective in improving blood pressure control, lowering LDL-C, and elevating HDL-C levels in people with diabetes. Physicians should recommend exercise for their adult patients with diabetes who can safely do so.
With permission from Excerpta Medica Inc.

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