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Resistance training and vibration improve muscle strength and functional capacity in female patients with multiple sclerosis
Eftekhari E, Mostahfezian M, Etemadifar M, Zafari A
Asian Journal of Sports Medicine 2012 Dec;3(4):279-284
clinical trial
5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

PURPOSE: The purpose of this study was to evaluate the effect of an eight-week progressive resistance training and vibration program on strength and ambulatory function in multiple sclerosis (MS) patients. METHODS: Twenty-Four female MS patients with the following demographics: age 27 to 45 years, and expanded disability status scale (EDSS) 2 to 4, participated in this study. The subjects were randomly allocated to one of two groups. The exercise group (n = 12) trained according to a progressive program, mainly consisting of resistance training and vibration, three times a week for eight weeks and compared with subjects in the control group (n = 12) that received no intervention. Subjects completed one set of 5 to 12 reps at 50 to 70% maximal voluntary contraction (MVC). After 5 to 10 minutes rest, six postures on plate vibration were done. Isotonic MVC of knee extensors, abduction of the scapula and downward rotation of the scapular girdle muscle groups were predicted by using the Brzycki formula. Right leg balance (RLB), left leg balance (LLB), and walking speed (10-meter walk test) were assessed before and after the training program. Descriptive statistics and co-variance were used for analyzing data. RESULTS: After eight weeks of training the exercise group showed significant increase in MVC of knee extensors (32.3%), abduction of the scapula (24.7%) and downward rotation scapular (39.1%) muscle groups, RLB (33.5%), LLB (9.5%), and decrease in 10-meter walk test (10MWT) (9.3%), p < 0.05. CONCLUSIONS: The results of this study indicated this type of training can cause improvements in muscle strength and functional capacity in patients with multiple sclerosis.

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