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| Effects of long-term moderate exercise and increase in number of daily steps on serum lipids in women: randomised controlled trial |
| Sugiura H, Sugiura H, Kajima K, Mirbod SM, Iwata H, Matsuoka T |
| BMC Women's Health 2002 Jan 21;2(3):Epub |
| clinical trial |
| 3/10 [Eligibility criteria: No; Random allocation: No; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
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BACKGROUND: This study was designed to evaluate the effects of a 24-month period of moderate exercise on serum lipids in menopausal women. METHODS: The subjects (40 to 60 y) were randomly divided into an exercise group (n = 14) and a control group (n = 13). The women in the exercise group were asked to participate in a 90-minute physical education class once a week and to record their daily steps as measured by a pedometer for 24 months. RESULTS: Mean of daily steps was significantly higher in the exercise group from about 6,800 to over 8,500 steps (p < 0.01). In the control group, the number of daily steps ranged from 5,700 to 6,800 steps throughout the follow-up period. A significant interaction between the exercise group and the control group in the changes of total cholesterol (TC), high-density lipoprotein cholesterol (HDLC) and (TC): HDLC ratio could be observed (p < 0.05). By multiple regression analysis, the number of daily steps was related to HDLC and TC: HDLC levels after 24 months, and the changes in TC and HDLC concentrations. CONCLUSIONS: These results suggest that daily exercise as well as increasing the number of daily steps can improve the profile of serum lipids.
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