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Bone health in children and adolescents with juvenile idiopathic arthritis and the influence of short-term physical exercise [with consumer summary]
Sandstedt E, Fasth A, Fors H, Beckung E
Pediatric Physical Therapy 2012 Summer;24(2):155-161
clinical trial
6/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

PURPOSE: To study bone mineral density (BMD) in 54 children and adolescents with juvenile idiopathic arthritis before and after a short-term exercise program. METHODS: Fifty-four children, 41 girls and 13 boys, median age 13.9 years, participated in a 12-week exercise program, with 33 children in an exercise group. The program consisted of one hundred 2-footed jumps with a rope and standardized muscle strength exercise. Both BMD and bone mineral content were assessed with dual-energy x-ray absorptiometry (DXA) and DXA Laser Calscan for the heel at the start and after 3 and 6 months. RESULTS: The study group had BMD measurements within the reference range compared with normative data with z-score at start. Bone mineral density values in total body, but not z-score, increased significantly (p = 0.012) in the exercise group. CONCLUSIONS: The study group had BMD measurements within the reference range. Twelve weeks of exercise increases BMD in children with juvenile idiopathic arthritis.
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