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| Effects of Qigong exercise on fatigue, anxiety, and depressive symptoms of patients with chronic fatigue syndrome-like illness: a randomized controlled trial |
| Chan JSM, Ho RTH, Wang C-W, Yuen LP, Sham JST, Chan CLW |
| Evidence-Based Complementary and Alternative Medicine 2013;(485341):Epub |
| clinical trial |
| 5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
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BACKGROUND: Anxiety/depressive symptoms are common in patients with chronic fatigue syndrome- (CFS-) like illness. Qigong as a modality of complementary and alternative therapy has been increasingly applied by patients with chronic illnesses, but little is known about the effect of Qigong on anxiety/depressive symptoms of the patients with CFS-like illness. PURPOSE: To investigate the effects of Qigong on fatigue, anxiety, and depressive symptoms in patients with CFS-illness. METHODS: One hundred and thirty-seven participants who met the diagnostic criteria for CFS-like illness were randomly assigned to either an intervention group or a waitlist control group. Participants in the intervention group received 10 sessions of Qigong training twice a week for 5 consecutive weeks, followed by home-based practice for 12 weeks. Fatigue, anxiety, and depressive symptoms were assessed at baseline and postintervention. RESULTS: Total fatigue score (F[1,135] = 13.888, p < 0.001), physical fatigue score (F[1,135] = 20.852, p < 0.001) and depression score (F[1,135] = 9.918, p = 0.002) were significantly improved and mental fatigue score (F[1,135] = 3.902, p = 0.050) was marginally significantly improved in the Qigong group compared to controls. The anxiety score was not significantly improved in the Qigong group. CONCLUSION: Qigong may not only reduce the fatigue symptoms, but also has antidepressive effect for patients with CFS-like illness. TRIAL REGISTRATION: HKCTR-1200.
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