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Interval and strength training in CAD patients
Helgerud J, Karlsen T, Kim WY, Hoydal KL, Stoylen A, Pedersen H, Brix L, Ringgaard S, Kvaerness J, Hoff J
International Journal of Sports Medicine 2011 Jan;32(1):54-59
clinical trial
5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

This study sought to study the effect of high intensity aerobic interval endurance training on peak stroke volume and maximal strength training on mechanical efficiency in coronary artery disease (CAD) patients. 8 CAD patients (age 61.4 +/- 3.7 years) trained 30 interval training sessions with 4x4 min intervals at 85 to 95% of peak heart rate while 10 CAD patients (age 66.5 +/- 5.5 years) trained 24 sessions of maximal horizontal leg press. In the interval training group peak stroke volume increased significantly by 23% from 94.1 +/- 23.0 mL/beat to 115.8 +/- 22.4 mL/beat (p < 0.05). Peak oxygen uptake increased significantly by 17% from 27.2 +/- 4.5 mL/kg/min to 31.8 +/- 5.0 mL/kg/min (p < 0.05) in the same group. In contrast, there was no such exercise training-induced change in peak stroke volume or peak oxygen uptake in the maximal strength training group, despite a 35% improvement in sub maximal walking performance.

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