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Effects of prolonged intensive versus moderate leg training on the untrained arm exercise response in angina pectoris |
Ben-Ari E, Kellermann JJ, Rothbaum DA, Fisman E, Pines A |
The American Journal of Cardiology 1987 Feb 1;59(4):231-234 |
clinical trial |
5/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
To compare the effects of 2 different leg training intensities on the cardiocirculatory exercise response of the untrained arm, 58 patients with angina pectoris were randomized to either an intensive (at least 85% of symptom-limited exercise, n = 28) or a moderate (70 to 85% of symptom-limited exercise, n = 30) training group. Patients trained for 6 months, 2 times per week for 30 minutes each. Results of the 2 groups after training showed similar significant (p <= 0.001) decreases in heart rate (HR), systolic blood pressure (BP) and HRxBP product for trained legs and untrained arms at matched subanginal workloads and significant (p < 0.01 to 0.001) increase in anginal threshold HR and HRxBP for the onset of 1 mm or more ST horizontal depression during testing of trained legs as well as of untrained arms. The improvement in exercise capacity at subanginal workloads results from decreased HR X BP product. In contrast, the significant increase in HRxBP product for the onset of ST-segment displacement and precipitation of anginal pain for both the trained and untrained limbs may imply an increase in myocardial blood flow. Thus, prolonged intensive or moderate training may significantly improve coronary blood flow in selected patients with angina pectoris. Patients with the highest anginal threshold HR and HRxBP product before training showed the most improvement at 6 months after training.
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