INTRODUCTION: Unfavorable lipid profile is associated with developed cardiovascular diseases. It is necessary to know the beneficial effects of different mode exercises to improve lipid profile. OBJECTIVE: To investigate, in obese men and women, the effect on lipid profile of hypocaloric diet combined with structured exercise programs or recommendations of physical activity. METHODS: Ninety six obese subjects (59 women and 61 men; 18 to 50 years; BMI > 30 and < 34.9 kg/m2) were randomised into four supervised treatment groups: strength training (S; n = 24), endurance training (E; n = 26), combined S+E (SE; n = 24), and and received recommendations of physical activity (PA; n = 22). Energy intake, body composition, training variables (VO2peak, strength index, dynamometric strength index) and blood lipid profile were recorded at baseline and after 24 weeks of treatment. RESULTS: Blood lipid profile improved in all groups. No statistically significant differences in baseline and posttraining values were observed between groups. HDL cholesterol showed no changes. A decrease in LDL cholesterol values was observed in all groups after the intervention (S 11.2%, E 10.8%, SE 7.9%, PA 10.8%; p < 0.01). S, E and PA subjects showed decrease in triglycerides (S 14.9%, E 15.8%, PA 15.7%; p < 0.01). Total cholesterol decreased in all groups (S 8.4%, p < 0.01; E 8.8%, p < 0.01; SE 4.9%, p < 0.01; PA 8.3%, p < 0.05). CONCLUSION: All protocols proposed in our study improved blood lipid profile in obese people. There were no significant differences about the effect on the lipid profile between the implementation of a structured training protocol with physical activity professional supervision and follow recommendations of physical activity.

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