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Three 15-min bouts of moderate postmeal walking significantly improves 24-h glycemic control in older people at risk for impaired glucose tolerance
di Pietro L, Gribok A, Stevens MS, Hamm LF, Rumpler W
Diabetes Care 2013 Oct;36(10):3262-3268
clinical trial
3/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: The purpose of this study was to compare the effectiveness of three 15-min bouts of postmeal walking with 45 min of sustained walking on 24-h glycemic control in older persons at risk for glucose intolerance. RESEARCH DESIGN AND METHODS: Inactive older (>= 60 years of age) participants (n = 10) were recruited from the community and were nonsmoking, with a BMI < 35 kg/m2 and a fasting blood glucose concentration between 105 and 125 mg/dL. Participants completed three randomly ordered exercise protocols spaced 4 weeks apart. Each protocol comprised a 48-h stay in a whole-room calorimeter, with the first day serving as the control day. On the second day, participants engaged in either (1) postmeal walking for 15 min or 45 min of sustained walking performed at (2) 10:30 am or (3) 4:30 pm. All walking was on a treadmill at an absolute intensity of 3 METs. Interstitial glucose concentrations were determined over 48 h with a continuous glucose monitor. Substrate utilization was measured continuously by respiratory exchange (VCO2/VO2). RESULTS: Both sustained morning walking (127 +/- 23 versus 118 +/- 14 mg/dL) and postmeal walking (129 +/- 24 versus 116 +/- 13 mg/dL) significantly improved 24-h glycemic control relative to the control day (p < 0.05). Moreover, postmeal walking was significantly (p < 0.01) more effective than 45 min of sustained morning or afternoon walking in lowering 3-h postdinner glucose between the control and experimental day. CONCLUSIONS: Short, intermittent bouts of postmeal walking appear to be an effective way to control postprandial hyperglycemia in older people.
Copyright American Diabetes Association. Reprinted with permission from The American Diabetes Association.

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