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Irradiation and health. A. ultra-violet irradiation of school children
Colebrook D
Special Report Series (Medical Research Council (Great Britain)) 1929;131:1-47
clinical trial
3/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: No; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

287 secondary school children of ages from five to seven inclusive were kept under medical observation from the end of August 1927 to the end of March 1928. 101 children were irradiated by light from a carbon arc lamp with a high output of ultra-violet rays. 94 children were exposed under exactly the same conditions to a similar lamp from which radiation of wave-length shorter than 3200 AU was cut off by window glass. 92 children received no irradiation. Record were kept of height and weight, of incidence and duration of colds and allied conditions, of attack rate of infectious diseases, of occurrence of chilblains, and of progress in school work. Comparison of these results shown: (a) for control and unscreened lamp groups, an advantage to the former group in every respect except in progress in school work in which the figures are equal; (b) for control and screened lamp groups, an advantage to the former group on every case except in incidence of whooping cough and progress in school work in which the advantage is to the screened lamp group; (c) for screened and unscreened lamp groups, an advantage to the former group in all points except the average 'duration per cold' in which the figures are equal, and gain in height in which the advantage is to the unscreened lamp group. The subjective impressions of the medical officer were indefinite; the balance of opinion was among the parents in favour of the unscreened group and among the teachers of both lamp groups, the screened lamp group taking first place. In many of the results, whether obtained by observation pr movement, or from subjective impressions, the numerical differences are very small and in no case are they large enough to signify either a harmful or a beneficial influence in either type of irradiation.

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