Use the Back button in your browser to see the other results of your search or to select another record.

Detailed Search Results

Home-based exercise training improves capillary glucose profile in GDM women
Halse RE, Wallman KE, Newnham JP, Guelfi KJ
Medicine and Science in Sports and Exercise 2014 Sep;46(9):1702-1709
clinical trial
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

PURPOSE: Regular maternal exercise may play an important role in the management of gestational diabetes mellitus (GDM); yet specific exercise guidelines to achieve glycaemic control have not been established. Furthermore, many women remain sedentary during pregnancy due to perceived barriers to exercise participation. This study examined the effectiveness of a home-based cycling program commenced upon diagnosis of GDM on daily fasting and postprandial blood glucose levels, glycosylated hemoglobin (HbA1c), as well as the response of glucose and insulin to a 75 g oral glucose load. METHODS: Forty sedentary women (28.8 +/- 0.9 weeks gestation) were randomized to either home-based exercise training, in combination with conventional management (EX; n = 20), or to conventional management alone (CON; n = 20) until week 34 of pregnancy. RESULTS: Mean compliance to the supervised exercise training was 96% and no adverse effects were reported. Capillary glucose concentration was acutely reduced in response to each cycling session (6.3 +/- 0.8 mmol/L to 4.9 +/- 0.7 mmol/L; p < 0.001). Overall, the EX group had lower mean daily postprandial glucose concentrations throughout the intervention compared with the CON group (p < 0.05) despite consuming a greater proportion of dietary carbohydrate (p < 0.05). No differences were observed between groups with respect to HbA1c or the glucose and insulin response to oral glucose ingestion post-intervention (p > 0.05). CONCLUSION: A home-based cycling program may help to maintain daily postprandial normoglycaemia in women with diet-controlled GDM.

Full text (sometimes free) may be available at these link(s):      help