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Effect of high-frequency chest wall oscillation versus chest physiotherapy on lung function after lung transplant |
Esguerra-Gonzales A, Ilagan-Honorio M, Kehoe P, Fraschilla S, Lee AJ, Madsen A, Marcarian T, Mayol-Ngo K, Miller PS, Onga J, Rodman B, Ross D, Shameem Z, Nandy K, Toyama J, Sommer S, Tamonang C, Villamor F, Weigt SS, Gawlinski A |
Applied Nursing Research 2014 Feb;27(1):59-66 |
clinical trial |
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
PURPOSE: The aim of this study is to compare the effects of chest physiotherapy (CPT) and high-frequency chest wall oscillation (HFCWO) on lung function in lung transplant recipients. BACKGROUND: Chest physiotherapy and HFCWO are routinely used after lung transplant to attenuate dyspnea, increase expiratory flow, and improve secretion clearance. METHODS: In a two-group experimental, crossover design with repeated-measures, 45 lung transplant recipients (27 single, 18 bilateral; 64% male; mean age 57years) were randomized to receive CPT at 10:00 AM and 2:00 PM followed by HFCWO at 6:00 PM and 10:00 PM (n = 22) or vice versa (n = 23) on postoperative day 3. Dyspnea (modified Borg score), SpO2/FiO2, and peak expiratory flow (PEF) were measured pre-treatment and post-treatment. Data were analyzed using Chi-square tests, t tests, and linear mixed effects models. RESULTS: There was no statistically significant treatment effect for dyspnea or PEF in patients who received HFCWO versus CPT. However, there was a significant treatment effect on the SpO2/FiO2 ratio (p < 0.0001). CONCLUSIONS: Preliminary results suggest that lung function (measured by SpO2/FiO2) improves with HFWCO after lung transplantation. Although dyspnea and PEF did not differ significantly between treatment types, HFCWO may be an effective, feasible alternative to CPT.
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