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Effects of whole-body vibration exercise training on aortic wave reflection and muscle strength in postmenopausal women with prehypertension and hypertension
Figueroa A, Kalfon R, Madzima TA, Wong A
Journal of Human Hypertension 2014 Feb;28(2):118-122
clinical trial
5/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

Increased wave reflection (augmented pressure (AP) and augmentation index (AIx)) and reduced muscle strength may increase cardiovascular risk in postmenopausal women. We evaluated the effects of whole-body vibration exercise training (WBVET) on aortic haemodynamics and leg muscle strength. Twenty-eight postmenopausal women (age 56 +/- 3 years; brachial systolic blood pressure (SBP) 138 +/- 12 mmHg; body mass index 33.9 +/13.7 kg/m2) were randomized to 6 weeks of WBVET (n = 15) or no-exercise control groups. Aortic SBP, diastolic blood pressure (DBP), pulse pressure (PP), AP, AIx, tension time index (TTI, myocardial oxygen demand) and leg press muscle strength were measured before and after 6 weeks. WBVET significantly (p < 0.05) decreased aortic SBP (about 10 mmHg), DBP (about 5 mmHg), PP (about 5 mmHg), AP (about 5 mmHg), AIx (about 10%) and TTI (about 311 mmHgs per minute), while increased muscle strength (about 9%) compared with no changes after control. Changes in AP and leg muscle strength were correlated (r = -0.58, p = 0.02). Our data demonstrated that WBVET reduced pressure wave reflection magnitude and aortic blood pressure in postmenopausal women with prehypertension or hypertension. Our study suggests that WBVET may decrease cardiovascular risk in postmenopausal women by improving wave reflection and muscle strength.
Reprinted by permission from Journal of Human Hypertension, Macmillan Publishers Ltd.

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