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Quadriceps strengthening exercises are effective in improving pain, function and quality of life in patients with osteoarthritis of the knee
Imoto AM, Peccin MS, Trevisani VFM
Acta Ortopedica Brasileira 2012 May;20(3):174-179
clinical trial
7/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: No; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: The purpose of this research was to verify the effectiveness of an eight-week quadriceps strengthening program on pain, function and quality of life of patients with knee osteoarthritis. METHODS: A hundred patients were randomized into two groups: (1) exercise group (ExG) and (2) orientation group. The Timed Up and Go (TUG) test, the numerical rating scale (NRS) and the Short Form-36 were used for the assessment. RESULTS: Eighty-one patients completed the survey. According to the intention to treat (ITT) analysis, there was statistically significant difference in ExG compared to OG in all the variables assessed. CONCLUSION: The program quadriceps strengthening exercises applied in this randomized clinical trial was effective in improving pain, function and quality of life of patients with knee osteoarthritis. LEVEL OF EVIDENCE: I, randomized clinical trial.

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