This study was designed to determine the effect of ground-based walking training on health-related quality of life and exercise capacity in people with chronic obstructive pulmonary disease (COPD). People with COPD were randomised to either a walking group that received supervised, ground-based walking training two to three times a week for 8 to 10 weeks, or a control group that received usual medical care and did not participate in exercise training. 130 out of 143 participants (mean +/- SD age 69 +/- 8 years, forced expiratory volume in 1 s 43 +/- 15% predicted) completed the study. Compared to the control group, the walking group demonstrated greater improvements in the St George's Respiratory Questionnaire total score (mean difference -6 points (95% CI -10 to -2), p < 0.003), Chronic Respiratory Disease Questionnaire total score (mean difference 7 points (95% CI 2 to 11), p < 0.01) and endurance shuttle walk test time (mean difference 208 s (95% CI 104 to 313), p < 0.001). This study shows that ground-based walking training is an effective training modality that improves quality of life and endurance exercise capacity in people with COPD.
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