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| Alimentary habits, physical activity, and Framingham global risk score in metabolic syndrome |
| Soares TS, Piovesan CH, Gustavo AS, Macagnan FE, Bodanese LC, Feoli AMP |
| Arquivos Brasileiros de Cardiologia 2014 Apr;102(4):374-382 |
| clinical trial |
| 4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
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BACKGROUND: Metabolic syndrome is a complex disorder represented by a set of cardiovascular risk factors. A healthy lifestyle is strongly related to improve quality of Life and interfere positively in the control of risk factors presented in this condition. OBJECTIVE: To evaluate the effect of a program of lifestyle modification on the Framingham general cardiovascular risk profile in subjects diagnosed with metabolic syndrome. METHODS: A sub-analysis study of a randomized clinical trial controlled blind that lasted three months. Participants were randomized into four groups: dietary intervention plus placebo (DIP), dietary intervention plus supplementation of omega 3 (fish oil 3 g/day) (DIS3), dietary intervention plus placebo plus physical activity (DIPE) and dietary intervention plus physical activity plus supplementation of omega 3 (DIS3PE). The general cardiovascular risk profile of each individual was calculated before and after the intervention. RESULTS: The study included 70 subjects. Evaluating the score between the pre and post intervention yielded a significant value (p < 0.001). We obtained a reduction for intermediate risk in 25.7% of subjects. After intervention, there was a significant reduction (p < 0.01) on cardiovascular age, this being more significant in groups DIP (5.2%) and DIPE (5.3%). CONCLUSION: Proposed interventions produced beneficial effects for reducing cardiovascular risk score. This study emphasizes the importance of lifestyle modification in the prevention and treatment of cardiovascular diseases.
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