OBJECTIVES: This systematic review was conducted to examine the current evidence regarding the effects of whole body vibration (WBV) training in individuals with knee osteoarthritis (OA). DATA SOURCES: We searched PubMed, CINAHL, Embase, Scopus, PEDro, and Science citation index for research articles published prior to January 2015 using the keywords whole body vibration, vibration training, and vibratory exercise in combination with medical subject headings "osteoarthritis knee". STUDY SELECTION: This meta-analysis was restricted to randomized controlled trials published in English language. The quality of the selected studies was assessed by the PEDro scale. The risk of bias was assessed using the Cochrane collaboration's tool in the domain based evaluation. We also evaluated the quality of each study based on the criteria given by the International Society of Musculoskeletal and Neuronal Interactions (ISMNI) for reporting WBV intervention studies, consisting of 13 factors. DATA EXTRACTION: Descriptive data regarding subjects, design, intervention, WBV parameters, outcomes, and conclusions were collected from each study by two independent evaluators. The mean and standard deviation of the baseline and final end point scores for pain, stiffness, and function were extracted from included studies. DATA SYNTHESIS: A total of 83 studies were found in the search. Of these, 5 studies met the inclusion criteria and were further analyzed. Four of these 5 studies reached high methodological quality on the PEDro scale. Overall, studies demonstrated mixed results in favor of additive effects of WBV for reducing pain and improving function in knee OA. There was considerable variation in the parameters of the WBV included in this systematic review. CONCLUSIONS: Whole body vibration training reduces pain and improves function in individuals with knee OA.

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