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Behavioral mediators of weight loss in the SHED-IT community randomized controlled trial for overweight and obese men |
Young MD, Lubans DR, Collins CE, Callister R, Plotnikoff RC, Morgan PJ |
Annals of Behavioral Medicine 2015 Apr;49(2):286-292 |
clinical trial |
5/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: No; Intention-to-treat analysis: Yes; Between-group comparisons: No; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
BACKGROUND: Little is known about which behavioral strategies are most important to target in weight loss interventions for men. PURPOSE: The aim of the current study was to identify behavioral mediators of weight loss in the male-only Self-Help, Exercise, and Diet using Information Technology (SHED-IT) community weight loss study. METHODS: A randomized controlled trial with 159 overweight/obese men (mean (SD) age 47.5 (11.0) years; body mass index 32.7 (3.5) kg/m2) assessed at baseline, 3 months (post-test) and 6 months (follow-up). RESULTS: In an intention-to-treat, multiple-mediator model, the significant intervention effect on weight at 6 months (-3.70 kg; p < 0.001) was mediated by increases in physical activity (steps/day) and decreases in takeaway meals (kJ/day) and portion size at 3 months. The largest mediation effect was for physical activity (-0.6 kg; 95% confidence interval -1.4 to -0.1). Overall, the targeted mediators accounted for 47.0% of the intervention's effect on weight. CONCLUSION: Step counts, takeaway food consumption, and portion sizes may be key areas to target in future weight loss programs for men (ACTRN12610000699066).
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