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Randomized controlled trial of web-based multimodal therapy for unilateral cerebral palsy to improve occupational performance [with consumer summary]
James S, Ziviani J, Ware RS, Boyd RN
Developmental Medicine and Child Neurology 2015 Jun;57(6):530-538
clinical trial
7/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

AIM: The study aimed to investigate the effectiveness of a web-based therapy programme, 'Move it to improve it' (Mitii), in children with unilateral cerebral palsy (UCP) on occupational performance, upper limb function, and visual perception. METHOD: Participants (n = 102) were matched in pairs and randomized to intervention (Mitii for 20 wks; 26 males, mean age 11 y 8 mo (2 y 4 mo), Manual Ability Classification System level I = 11, II = 39, III = 1) or control (standard care; 25 males, mean age 11 y 10 mo (2 y 5 mo), Manual Ability Classification System level I = 13, II = 37). Outcomes were the Assessment of Motor and Process Skills (AMPS), Assisting Hand Assessment, Jebsen-Taylor Test of Hand Function (JTTHF), Melbourne Assessment of Unilateral Upper Limb Function (MUUL), Canadian Occupational Performance Measure (COPM), and Test of Visual Perceptual Skills (TVPS-3). RESULTS: Participants completed on average 32.4 hours of Mitii (range 3.7 to 74.7 h). The Mitii group demonstrated significantly greater post-intervention scores than the comparison group on the AMPS, JTTHF dominant upper limb, COPM, and TVPS-3. The differences between groups were not clinically significant. There were no differences between groups on measures of impaired upper limb function. INTERPRETATION: Mitii delivers individualized, web-based therapy at home and has potential to increase therapy dose. Mitii can be considered as an option to enhance occupational performance and visual perception for children with UCP.

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