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Single-blinded, randomised preliminary study evaluating the effects of 2 Hz electroacupuncture for postoperative pain in patients with total knee arthroplasty [with consumer summary]
Tzeng C-Y, Chang S-L, Wu C-C, Chang C-L, Chen W-G, Tong K-M, Huang K-C, Hsieh C-L
Acupuncture in Medicine 2015 Aug;33(4):284-288
clinical trial
6/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: To explore the point-specific clinical effect of 2 Hz electroacupuncture (EA) in treating postoperative pain in patients undergoing total knee arthroplasty (TKA), METHODS: In a randomised, partially single-blinded preliminary study, 47patients with TKA were randomly divided into three groups: control group (CG, n = 17) using only patient-controlled analgesia (PCA); EA group (EAG, n = 16) with 2 Hz EA applied at ST36 (Zusanli) and GB34 (Yanglingquan) contralateral to the operated leg for 30 min on the first two postoperative days, also receiving PCA; and non-point group (NPG, n = 14), with EA identical to the EAG except given 1 cm lateral to both ST36 and GB34. The Mann-Whitney test was used to show the difference between two groups and the Kruskal-Wallis test to show the difference between the three groups. RESULTS: The time until patients first required PCA in the CG was 34.1 +/- 22.0 min, which was significantly shorter than the 92.0 +/- 82.7 min in the EAG (p < 0.001) and 90.7 +/- 94.8 min in the NPG (p < 0.001); there was no difference between the EAG and NPG groups (p > 0.05). The total dosage of PCA solution given was 4.6 +/- 0.9 mL/kg body weight in the CG, 4.2 +/- 1.0 mL/kg in the EAG and 4.5 +/- 1.0 mL/kg in the NPG; there were no significant differences (p > 0.05) among the three groups. CONCLUSIONS: In this small preliminary study, EA retarded the first demand for PCA in comparison with no EA. No effect was seen on the total dosage of PCA required and no point-specific effect was seen.

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