OBJECTIVE: We performed a systematic review and meta-analysis to assess the effect of cognitive motor intervention (CMI) on gait and balance in Parkinson's disease. DATA SOURCES: PubMed, Embase, Cochrane Library, CINAHL, Web of Science, PEDro, and China Biology Medicine disc. METHODS: We included randomized controlled trials (RCTs) and non RCTs. Two reviewers independently evaluated articles for eligibility and quality and serially abstracted data. A standardized mean difference +/- standard error and 95% confidence interval (CI) was calculated for each study using Hedge's g to quantify the treatment effect. RESULTS: Nine trials with 181 subjects, four randomized controlled trials, and five single group intervention studies were included. The pooling revealed that cognitive motor intervention can improve gait speed (Hedge's g = 0.643 +/- 0.191; 95% CI 0.269 to 1.017, p = 0.001), stride time (Hedge's g = -0.536 +/- 0.167; 95% CI -0.862 to -0.209, p = 0.001), Berg Balance Scale (Hedge's g = 0.783 +/- 0.289; 95% CI 0.218 to 1.349, p = 0.007), Unipedal Stance Test (Hedge's g = 0.440 +/- 0.189; 95% CI 0.07 to 0.81, p = 0.02). CONCLUSIONS: The systematic review demonstrates that cognitive motor intervention is effective for gait and balance in Parkinson's disease. However, the paper is limited by the quality of the included trials.

Full text (sometimes free) may be available at these link(s):      help

• DOI
• PubMed
• PDF locator
• publisher