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Effects of treadmill training with load on gait in Parkinson disease: a randomized controlled clinical trial
Trigueiro LCL, Gama GL, Simao CR, de Sousa AVC, Godeiro Junior CO, Lindquist ARR
American Journal of Physical Medicine & Rehabilitation 2015 Oct;94(10 Suppl 1):830-837
clinical trial
5/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: The aim of this study was to assess the effects of 3% of body weight loads (0%, 5%, and 10%) on treadmill gait training in subjects with Parkinson disease. DESIGN: This study used a randomized controlled single-blind trial. RESULTS: Spatiotemporal variables demonstrated significant intragroup alterations in all three groups at pretraining and posttraining, with an increase in speed (m/sec; F = 4.73, p = 0.04), stride length (m; F = 12.00, p = 0.002), and step length (m; F = 16.16, p = 0.001) and a decrease in the double-stance phase (%; F = 6.59, p = 0.02) and stance phase (%; F = 4.77, p = 0.04). Intergroup pretraining and posttraining did not exhibit significant differences (F < 2.18, p > 0.14). Angular variables showed significant intragroup alterations, with an increase in knee range of motion (F = 5.18, p = 0.03), and intergroup comparison revealed no significant changes (F = 1.87, p = 0.17). CONCLUSIONS: Posttraining improvements in speed, stride length, step length, double-stance, stance phase, and knee range of motion were observed in all groups, where no load (0%, 5%, or 10%) had any significant effect, suggesting that the influence of load did not make one experimental condition better than another. All participants benefitted from treadmill gait training, irrespective of the use of load.

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